JACEK JEMIELITY

 

 

Employment

2013 – now

Professor and Group Leader of Laboratory of Bioorganic Chemistry, Centre of New Technologies University of Warsaw, Poland

2002 – 2013

Assistant Professor, Div. of Biophysics, Faculty of Physics, University of Warsaw, Warsaw, Poland

Research Experience

August 2002

One month training in dr Jadwiga Chroboczek group at Institute of Structural Biology, Grenoble,
France

June-August 2003

Three-month training in prof. Harri Lonnberg group in University of Turku, Turku, Finland

Education

Professor

2020

University of Warsaw

Habilitation, Bioorganic Chemistry

2012

University of Warsaw, Faculty of Chemistry

Ph.D., Chemistry

2002

University of Warsaw, Faculty of Chemistry

M.Sc., Organic Chemistry

1997

Faculty of Chemistry

Publications

Co-author of >140 publications
H-index: 29
Number of citations: 2550
Complete bibliographic data available with ORCID number: 0000-0001-7633-788X

 

 

Patents

Jemielity J., Grudzien-Nogalska E., Kowalska J., Darzynkiewicz E., Rhoads R.E “Synthesis and use of anti-
reverse phosphorothioate analogs of the messenger RNA cap” – patent family including patents issued in
the US (2012), Poland (2013), Eurasia, Australia, and China. Licensed to BioNTech AG in 2010 and applied
in several clinical trials (mRNA based anticancer vaccines).

• Kowalska J. Jemielity J., Darżynkiewicz E., Rhoads R.E., Lukaszewicz M., Zuberek J. “mRNA Cap Analogs” US
patent family including patents issued in the US (2013), Poland (2013), Eurasia, and Australia. Licensed to
BioNTech AG in 2010.
4 other international patents
3 filled PCT patent applications

 

 

Research support

2020-2021 NCN UMO/2020/01/0/ST4/00124 PI: Jemielity
Grant from the National Center of Science (Poland)
SARS-CoV-2 mRNA capping machinery – studies on nsp14 and nsp16 methyltransferase activity using highthroughput fluorescence method

2020-2023 NCN 2019/33/B/ST4/01843 PI: Jemielity
Grant from the National Center of Science (Poland) mRNA 5′ end methylation status: towards deeper understanding of biological role and identification of synthetic mimics

2017-2020 NCN UMO-2016/21/B/ST5/02556 PI: Jemielity
Grant from the National Center of Science (Poland) Chemically modified mRNA for studies on cellular processes and therapeutic applications

2017-2022 FNP TEAM 2/2016 PI: Jemielity
Grant from The Foundation for Polish Science. New selective inhibitors of cap dependent proteins: synthesis, delivery and characterization

Awards and Distinctions

• FNP Prize Laureate in Chemistry 2021 for developing chemical modifications of mRNA as tools for
therapeutic applications and studies on cellular processes. (2021)
• Nomination to the European Inventor Award organized by European Patent office (nomination in
research category together with Joanna Kowalska, Edward Darżynkiewicz and the team, 2018)
• Honorary badge form Prime Minister of Poland “For merits for inventiveness” (2018)
• President’s of Poland Economy Award (research category; together with Joanna Kowalska, Edward
Darżynkiewicz and the team, 2017)
• Scientific Award for Young Scientists of the “Polityka” Foundation (VIII Edition). (2008)
• Rector Grzegorz Bialkowski Award from the Faculty of Physics, University of Warsaw for “Designing and
chemical synthesis of mRNA cap analogues and biophysical studies of their interaction with protein
factors”. (2008)
• University of Warsaw Rector’s award (1st degree) for scientific achievements (2018 and 2021)
• University of Warsaw Rector’s award (2nd degree) for scientific achievements (2011)
• University of Warsaw Rector’s award (3rd degree) for scientific achievements (2004